{"id":167,"date":"2026-03-23T12:06:41","date_gmt":"2026-03-23T03:06:41","guid":{"rendered":"https:\/\/emin.okayama-u.ac.jp\/?page_id=167"},"modified":"2026-08-06T13:07:27","modified_gmt":"2026-08-06T04:07:27","slug":"core01","status":"publish","type":"page","link":"https:\/\/emin.okayama-u.ac.jp\/en\/core01\/","title":{"rendered":"Radiotheranostics &#038; Precision Medicine Innovation Core"},"content":{"rendered":"<h2>Introduction<\/h2>\n<p>This research core is dedicated to advancing the emergence of precision medicine grounded in radiopharmaceutical science.<\/p>\n<p>Building upon Okayama University\u2019s internationally recognized achievements and strengths established through regional industry\u2013academia\u2013government collaboration initiatives, the core promotes radiopharmaceutical-based drug discovery and the development of advanced imaging technologies, with a central focus on theranostics, which integrates diagnosis and therapy.<\/p>\n<p>By visualizing disease processes at the molecular level and translating these insights into optimized treatments for individual patients, the core serves as a central hub for next-generation medical innovation.<\/p>\n<h2>Research Overview<\/h2>\n<h3>1. Development of 18F-Labeled PET Imaging Agents.<\/h3>\n<p>We develop high-performance PET tracers labeled with 18F and other positron-emitting radionuclides, including small molecules, peptides, antibodies, and nanoparticle-based probes, enabling precise molecular visualization of disease.<\/p>\n<h3>2. Radiopharmaceutical Design and Optimization Platform.<\/h3>\n<p>We establish advanced platforms for molecular engineering, radiolabeling chemistry, and pharmacokinetic optimization to enhance target specificity and in vivo performance of imaging and therapeutic agents.<\/p>\n<h3>3. Targeted Radiotherapeutics.<\/h3>\n<p>We develop therapeutic radiopharmaceuticals incorporating beta- and alpha-emitting radionuclides to achieve precise and effective targeted radiotherapy.<\/p>\n<h3>4. Theranostic Integration and Personalized Dosimetry.<\/h3>\n<p>By integrating diagnostic and therapeutic isotopes, we design patient-specific treatment strategies guided by imaging biomarkers and quantitative dosimetric analysis.<\/p>\n<h3>5. Translational Advancement and Clinical Implementation.<\/h3>\n<p>We promote seamless translation from preclinical validation to clinical application, accelerating the development of next-generation radiopharmaceuticals from bench to bedside.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Introduction This research core is dedicated to advancing the emergence of precision medicine grounded in radiopharmaceutical science. 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